Suppositories are solid dosage forms intended for rectal or vaginal administration. Depending on the medication and base used, they may provide either local or systemic therapeutic effects.

Determine the total number of suppositories required and calculate the amount of active ingredient needed. Account for displacement factors when applicable.

The standardized cavity sizes found in TICKERWORKS molds simplify these calculations and help improve consistency from batch to batch.

Heat the selected suppository base until it reaches a smooth, pourable consistency. Avoid overheating, as excessive temperatures may affect heat-sensitive ingredients.

Levigate or dissolve the active pharmaceutical ingredient according to the formulation requirements. Thorough mixing is essential to promote uniform distribution throughout the batch.

Pour the prepared formulation onto the mold surface, then use a spatula to spread the mixture across the cavities. The TICKERWORKS Pour & Dispense™ design allows multiple cavities to be filled simultaneously, helping pharmacies produce uniform troches faster and more efficiently than traditional cavity-by-cavity filling methods.

Allow suppositories to solidify completely before removal from the mold.

TICKERWORKS molds are designed for easy release, helping reduce breakage and minimize waste during demolding.

Package to maintain stability and protect from heat exposure.

For maximum convenience and protection, many pharmacies to package in standard plastic prescription bottles or individual blister packaging. Ensure proper temperature control as suppositories need to be protected from moisture, excessive light, and high temperatures.